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Brodifacoum
Brodifacoum
Supplier Info
[China Supplier]
Contact Person : Mr. Yan Steven
Tel : 86-511-85210316
Fax : 86-511-85222589
Product Detail
1)Brodifacoum 98%TC 2)Quality Certificate by SGS 3)Fine packet or as per requirement 4)Competitive price.

APPLICATIONS Biochemistry Inhibits the vitamin K-dependent steps in synthesis of clotting factors II, VII, IX and X.  Mode of action Indirect anticoagulant.  Uses Controls most rodent pests, including Rattus norvegicus, R. rattus and Mus musculus at lower rates than many other anticoagulants (e.g. warfarin and pindone); also Cricetus cricetus, Mesocricetus auratus, Microtus pennsylvanicus, M. pinetorum, R. argentiventer, R. rattus mindanensis and rodents, such as hamsters, that are difficult to control with other anticoagulants. Potency is such that a rodent may absorb a lethal dose by taking a 50 mg/kg bait as part of its food intake on only one occasion. For a review, see A. P. Buckle & R. H. Smith, "Rodent Pests and their Control", CABI (1994).  Formulation types AB; BB; RB.  Selected tradenames: 'Havoc' (Syngenta); 'Klerat' (Syngenta); 'Sorex Brodifacoum Rat & Mouse Bait' (Sorex); 'Talon' (Syngenta)

ANALYSIS Product analysis by hplc (CIPAC Handbook, 1985, 1C, 1981; AOAC Methods, 1995, 983.11; Anal. Methods Pestic. Plant Growth Regul., 1988, 16, 134). Residues determined by hplc (idem, ibid.). Details from Syngenta. 

MAMMALIAN TOXICOLOGY Oral Acute oral LD50 for male rats 0.4, male rabbits 0.2, male mice 0.4, female guinea pigs 2.8, cats c. 25, dogs 0.25-3.6 mg/kg.  Skin and eye Acute percutaneous LD50 for rabbits 0.25-0.63 mg/kg. Slight to mild skin and eye irritant (rabbits). A moderate skin sensitiser (guinea pigs), but negligible risk of sensitisation from formulated product.  Inhalation LC50 (4 h) 5 mg/l air.  NOEL 0.02 mg/kg diet daily.  Toxicity class WHO (a.i.) Ia; EPA (formulation) I  EC hazard T+; R27/28| T; R48/24/25| N; R50, R53 

ECOTOXICOLOGY Birds Acute oral LD50 for Japanese quail 11.6, chickens 4.5, mallard ducks 0.31 mg/kg. Dietary LC50 (40 d) for mallard ducks 2.7, bobwhite quail 0.8 ppm.  Fish LC50 (96 h) for bluegill sunfish 0.165, rainbow trout 0.051 mg/l.  Daphnia LC50 (48 h) 0.34 mg a.i./l (as formulation). 

ENVIRONMENTAL FATE EHC 175 (WHO, 1995).  Animals In mammals, a number of hydroxycoumarins are formed.  Soil/Environment Degraded in soils (pH 5.5 to pH 8) under aerobic and flooded conditions. Koc (average) 50 000, range 14 000-106 000; Kd 1040 (average), range 625-1320. DT50 >12 w. Unlikely to leach; <2% leached >2 cm in laboratory columns. 

Brodifacoum

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