Warfarin 97%TC Detailed Product Description

Warfarin TechClassification: Rodenticide

Common name

warfarin (BSI, E-ISO, BAN); warfarine ((m) F-ISO); coumafène (France); zoocoumarin (USSR); coumarins (JMAF, also applied to coumatetralyl (q.v.)); no name (The Netherlands)

IUPAC name

(RS)-4-hydroxy-3-(3-oxo-1-phenylbutyl)coumarin; 3-(a-acetonylbenzyl)-4-hydroxycoumarin 

Chemical Abstracts name

4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one 

CAS RN   

[81-81-2] unstated stereochemistry; [5543-58-8] (R)-(+)- isomer; [5543-57-7] (S)-(-)- isomer

Formulation types:AB; CB; CP; GB; RB; Gel. 

Molecular formula: C19H16O4 

Molecular weight: 308.3

Properties:

The racemate forms colourless crystals.

Toxicity: Oral Acute oral LD50 for rats 186, mice 374 mg/kg. Oral LD50 for rats 1, pigs 1, cats 3, dogs 3, cattle 200 (all mg/kg daily for 5 days).  Other Organ damage is observed, as well as inhibition of blood coagulation. Only slightly dangerous to humans and domestic animals when used as directed, but care must be taken with young pigs, which are especially susceptible.  Toxicity class WHO (a.i.) Ib; EPA (formulation) I  EC classification R61| T; R48/25| R52, R53 (for (R)-, (S)-, or (RS)- isomers) 

Uses:

Anticoagulant rodenticide. Repeated ingestion is necessary to produce toxic symptoms. The (S)-(-)- isomer has 7-fold greater rodenticidal activity than the (R)-(+)- isomer (B. D. West et al., J. Am. Chem. Soc., 1961, 83,2676).  Control of rats and mice. There is no tendency to bait-shyness.

warfarin rodenticide