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Introduction:
Hyaluronic acid(HA) is a straight chain macromolecular mucopolysaccharide composed of repeat disaccharide units of glucuronic acid and N-acetylglucosamin. It widely consists in the extracellular space of human and animal tissue, vitreum, umbilical cord, skin joints synovia and cockscomb, etc. The commercial HA is commonly a sodium salt, called sodium hyaluronate, habitually called hyaluronic acid. HA is a new biological at home and abroad. Its molecular weight is from several ten thousand to several million. It's aqueous solution has outstanding moisture keeping ability, high viscoelasticity and lubricity.
Function:
1, Improving joint function
2, Natural moisturizing lubricant
3,It can prevent arteriosclerosis, pulse disorder and the occurrence of the disease such as the brain atrophy.
4.It is widely used in cosmetics 5.moisture retain 6.anti-ageing, lotion,cream
Specification:
a.Food grade b.Cosmetic grade c.Eye drop grade d.Injection grade
Flow Chart of HA Production
1.Raw materials
2.Sterilization
3.Fermentation
4.Filtration
5. Absorption
6. CPC Isolation
7. Ethanol precipitation
8. Dewatering
9. Drying
10.Packing
Certificate Of Analysis:
cosmetics grade
Appearance | White powder | White powder |
Glucuronic Acid (%) | ≥44.0 | 46.29 |
Sodium hyalunate (%) | ≥91.0 | 95.68 |
Transparency(0.1% aqueous solution) | ≥99.0 | 99.9 |
pH(0.1% aqueous solution) | 6.0-7.5 | 6.54 |
Molecular Weight (Da) | (0.8-2.0)*106 | 1.34*106 |
Protein,% | <0.05 | 0.020 |
Loss on Drying | ≤10.0 | 6.74 |
Residue on Ignition, % | ≤20 | 14.85 |
Heavy Metal(as Pb), ppm | <20 | <10 |
Arsenic,ppm | <2 | <2 |
Bacteria Count,cfu/g | <100 | <10 |
Molds & Yeast, cfu/g | <10 | <10 |
Staphylococcus aureus | Negative | Negative |
Pseudomonas aeruginosa | Negative | Negative |
Hemolysis | Negative | Negative |
Viable Hemolytical Streptococci | Negative | Negative |
Other Indexes of Microorganism | Accord with The National Standard | |
Conclusion | Up to grade | |
Sodium Hyaluronate Cosmetic Grade