HFC-134a is the substitution of CFC-12 in refrigeration, polymer foaming, acrosol producing, etc., which is widely used in automobile air-conditioning, home applications, small fixed refrigerators, medium-temperature refrigerators in supermarkets and industrial refrigerators.　　As the research carrying on, HFC-134a is to be used as carrier of pharmaceutical inhalation. HFC-134a could also be used in the aerosol production with extreme limitation in toxicity and flammability.