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| MEGLUMINE | ||
PRODUCT IDENTIFICATION | ||
| CAS NO. | 6284-40-8 | |
| EINECS NO. | 228-506-9 | |
| FORMULA | CH3NHCH2(CHOH)4CH2OH | |
| MOL WT. | 195.22 | |
H.S. CODE | 2922.19 | |
TOXICITY | ||
| SYNONYMS | 1-Deoxy-1-methylaminosorbitol; N-Methyl-d-glucamine; | |
| DERIVATION | ||
CLASSIFICATION | ||
PHYSICAL AND CHEMICAL PROPERTIES | ||
| PHYSICAL STATE | white powder | |
| MELTING POINT | 128 - 132 C | |
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| pH | ||
| VAPOR DENSITY | ||
AUTOIGNITION | 350 C | |
NFPA RATINGS | Health: 0; Flammability: 0; Reactivity: 1 | |
REFRACTIVE INDEX | ||
| FLASH POINT | ||
| STABILITY | Stable under ordinary conditions | |
GENERAL DESCRIPTION AND APPLICATIONS | ||
| Glucamine, 1-amino-1-deoxy-D-sorbitol, is an amine formed by reduction of glucosylamine or glucose oxime. N-alkylated glucamines are prepared from D-glucose and relevant alkylamines. Meglumine is N-methyl glucamine, a derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. It is a white crystalline powder; melting at 130 C. Meglumine is used in the preparation of certain radiopaque media such as diatrizoate meglumine and iodipamide meglumine. Meglumine is combined as an excipient (an inert substance) not an active ingredient. Excipients are added to ensure that the shelf-life of the active ingredients can be long enough to be active until internal use. Excipients are combined also to support the active ingredients, so that the latter can be easily administered or absorbed in the body. Examples of meglumine-combined drugs are flunixin meglumine (non-steroidal anti-inflammatory drugs, used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis). Meglumine is used in ion-exchange resins to chelate boron ions selectively. N-alkyl glucamines are used in preparing functional surfactants and some solutions which are stable over a wide range of pH and ionic strength. | ||
| SALES SPECIFICATION | ||
APPEARANCE | white powder | |
ASSAY | 99.0% min | |
OPTICAL ROTATION | -15.5° ~ -17.5° | |
LOSS ON DRYING | 0.5% max | |
| TRANSPORTATION | ||
| PACKING | 25kgs in fiber drum | |
| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: , Risk Phrases: , Safety Phrases: 24/25 | ||
MEGLUMINE(N-Methyl-d-glucamine)