Ads by Google
Product Information | |
Product Name | Docetaxel Anhydrous 99.8% |
Molecular Formula | C43H53NO14 (807.88) |
Cas No. | 114977-28-5 |
Quality standard | complies with In-house Standard |
Analysis | Standard |
Assay(W/W) | 98.0-102.0% |
Purity(HPLC) | ≥99.8% |
Physical Control | |
Appearance | White crystalline powder |
Identification | Conforms |
Specific Optical Rotation | -40°~-47° |
Water | ≤3.0% |
Chemical Control | |
Residue of solvents | Complies with ICH requirement |
Residue on Ignition | NMT0.2% |
Bacteria Endotoxins | 0.4EU/MG |
Heavy Metal | NMT20ppm |
Chromatographic Impurities | |
Highest Individual Impurity | NMT0.1% |
Unknown Impurity | NMT0.1% |
Total Impurity | NMT0.5% |
Microbiological Control | |
Total Aerobic Microbial Count | NMT 100cfu/g |
S.Aureus & Aeruginosa | Negative |
Salmonella & E.Coil | Negative |
Storage | |
Store at 2-8°C, In well closed containers and protect from light and moisture | |
Physical Properties:
melting point 232 , soluble in ethanol, acetone, ethyl acetate, almost insoluble in water
Pharmacological effects: breast cancer and non-small cell carcinoma,
bioavailability, and side effects of small
Product Source :
Polyunsaturated Taxol is paclitaxel in the process of structural transformation of taxol
from derivatives
Application:
Docetaxel (trade name Taxotere) is a clinically well established anti-mitotic chemotherapy medication (that is, it interferes with cell division). It is used mainly for the treatment of breast, ovarian, and non-small cell lung cancer. Docetaxel has an FDA approved claim for treatment of patients who have locally advanced, or metastatic breast or non small-cell lung cancer who have undergone anthracycline-based chemotherapy and failed to stop cancer progression or relapsed.[ and a European approval for use in hormone-refractory prostate cancer.
Packing: 1kg/one bag or 5kg/one bag,25kg/Fiber,or at your requirment.
Double plastic bag of foodstuff inside, cardboard drum outside.Shelf Life: 2 years when properly stored.Storage: Store in Cool and dry place,keep away from strong light, hight temperature.
Docetaxel