1.Bortezomib: 2.CAS: 179324-69-7 3.MF: C19H25BN4O4 4.MW: 384.24 Name: BortezomibSynonyms: boronic:acid; Velcade; DPBAMolecular Formula: C19H25BN4O4Molecular Weight :384.24CAS:179324-69-7Loss on drying: ≤0.5% 0.1% Burned ash: ≤0.1% 0.08% Heavy Metals: ≤20ppm Complies Assay (HPLC): ≥98.5% 99.1%Usage: Bortezomib is the first therapeutic proteasome inhibitor to be tested in humans. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.  Product line

Items	Requirements	Results
Description	White needle crystalline or crystalline powder ,easily soluble in ethanol ,slightly soluble in water .	Conformity
Melting point	113°C~118°C	116°C
Optical rotation	-60.~-70.	-60.
Identification	(1) Conformity	Conformity
	(2) Conformity	Conformity
Related Substance	not more than5.0%	3.0%
Loss on Drying	not more than 1.0%	0.8%
Contents (HPLC method)	95.0%~105.0%	99.7%

 

Bortezomib CAS:179324-69-7