Indomethacin CAS No.: 53-86-1 MF: C19H15ClNO4 EINECS No.: 200-186-5
This product has obvious effect on anti-inflammation and antipyretic, can be easily absorbed and excreted. It can be fully absorbed after taken orally in the gastrointestinal tract, and in 1-4 hours the plasma concentration will reach a peak; it will be excreted by liver metabolism, with the urine. Analgesic effects on inflammatory pain there, and its mechanism of inhibiting prostaglandin synthesis. Salicylic acid is mainly used on the efficacy of drugs difficult to tolerate, or not significant rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and so on. Can also be used for acute gout and cancer, fever, or other difficult to control fever.
Item | Standard | Result |
Appearance | White or yellow crystalline powder | Conforms |
Identification | Positive | Conforms |
Melting point | 158-162 | 159-160 |
Absorption at 318nm | 170-190 | 185.6 |
Related substances(TLC) | ≤0.5% | 0.5% |
Loss on drying | ≤0.5% | 0.07% |
Sulphated ash | ≤0.1% | 0.03% |
Heavy metals | ≤20ppm | 20ppm |
Related solvent | ≤0.5% | 0.5% |
Content | 98.5-100.5% | 99.8% |
GMP certified Indomethacin powder & capsules