Honeysuckle extract 25%,50%,98% 1> Extract from Honeysuckle 2> Chlorogenic Acid 14% 3> CAS No. 327-97-9

Honeysuckle extract 25%,50%,98%Product Name: Honeysuckle Flower P.E.

English byname: Chlorogenic acidChemical name: 3-O-caffeoylquinic acidCAS No.: 327-97-9Molecular Formula: C16H18O9Molecular Weight: 354.31 Plant originChlorogenic acid is a phenolic natural product isolated from the leaves and fruits of dicotyledonous plants, including the coffee beanLythrum salicaria Dodonaea viscose (L.)Jacp. Polypodium vulgare L.Stachytarpheta jamaicensis(L.)VahlBrassica oleracea L.var.capitata L.Polygonum aviculare L.Galium verum L. and Sambucus javanica Reinw. Main functions1About pharmacodynamics study It is investigated that chlorogenicacid has a poor absorption when taken by mouth with a little part of which absorbed in small intestine while most of it will be absorbed in the terms of benzoic acid acid exists in the form of metabolites in the blood plasma. Protein binding: It is proved by test in vitro that chlogogenic acid can bind with HAS in different concentration. There is only one combine site in low concentration. It appears to be several sites in high concentration in the region of HAS and IIA. Excretion: chlogogenic acid and its metabolites in blood plasma mainly discharged through kidney but discharged along with urine when it taken by mouth.and benzene propanoic acid and cinnamic acid. Therefore chlorogenic 1) The protection to cardiovascular A large number of experiments have show that Chlorogenic acid, as a kind of free radical scavenger and antioxidant, has a good protection to cardiovascular. Chang Cuiqing proved that chlorogenic acid has a preparatory prevention to the damage of endothelial cells induced by ox-LDL. Chlopcikova discovered that chlorogenic can protect Myocardium cell from being damaged by oxidant of Doxombiein,DOx and has a prominent inhibition of peroxidization of mitochondria envelope lipid induced by iron reserves dependence DOX. It goes to show chlorogenic acid can protect vascular endothelium cell by removing radical intermediate and antioxidant lipids and has a further prevention to arteriosclerosishypertension and thrombosis. 2) Anti-mutagens and anti-cancer The experiment of animals shows that chlorogenic acid can prevent and inhibit colon cancer and stomach cancer. Jiang discovered chlorogenic acid brought bigger DNA fragments produced by tumor cells and its agglutination. Aryl hydrocarbon hydroxylase is an important Metabolizing Enzyme of polynuclear aromatic and its activeness would improve the mutagens of anti- polynuclear aromatic of tissue cells. Research in vitro discovered that chlorogenic acid can improve the activeness of Aryl hydrocarbon hydroxylase. It also can inhibit the formation of 8-OHdG and the grow of Escherichia foetidaStaphylococcus aureusblack hay bacillus and legionella. 3) Reduce blood fatVeins have given chlorogenic the power of reducing cholesterol and triglycerides in the blood of rats. When adding chlorogenic acid to the food of rats, it discovered that the cholesterol in rats lungs and livers has also reduced. 4) Anti-leukemia Chiang found that chlorogenic acid had light activeness of anti-leukemia by the experiment in vitro. J. Bandyopadhyay has proved that chlorogenic acid can inhibit Ber-Abl and c-Abl and induce the dead of the original lymphocytosis in the body of leukemia patients. 5) Adjust the immune function The research in vitro has showed chlorogenic acid can obviously strengthen T cells caused by influenza as well as induce humans lymphocytes and albumen cells to produce 7-IFN and α-IFN. It can improve the lgG1 and Ll4 level of rats. In a recent research, it is discovered that chlorogenic acid has the ability to activate nerve cardiac troponin to strengthen the function of macrophages. 6) Lower glucose It is proved by the research of Andrade-Cetto and Wiedenfeld H thatChlorogenic acid has potential function in lowering glucose in animals body. The function may have relationships with the inhibiting of glucose-6- and the absorption of glucose.0

Honeysuckle extract 25%,50%,98%

Verified Information This information is Verified by Bureau Veritas and validity period is 2012/10/19 --- 2013/10/19 All the information below may covers both Gold Supplier and its related companies , Their Relationship will be affirmed according to china laws and regulations , also it will be clearly display in the full report >> Production Capacity: Product line name Production Line Capacity Actual Units Produced(Previous Year)

Instant tea powder series, Tea polyphenols, EGCG, Resveratrol, DNJ, Sulforaphane, Chlorogenic acid, Rose extract, Guarana extract, Tea tree oil, Eucalyptus oil, Peppermint oil, Cajuput essential oil, Kiwi seed oil, Sweet almond oil	N/A	N/A

Export Market Distribution: Market Revenue(Previous Year) Total Revenue (%)

North America	confidential	45.0
Southeast Asia	confidential	15.0
Africa	confidential	5.0
Oceania	confidential	5.0
Mid East	confidential	30.0

Testing Machinery: Machine Name Brand & Model No. Quantity Number of Year(s) Used Condition

Drying Oven	DZF-6050/101Z	2	5.0	Acceptable
Analytical Balance	FA1004B	1	5.0	Acceptable
PH Tester	PHB-3	1	5.0	Acceptable
UV/IVS Detector	SPD-20A/LC-20AT	2	1.0	Acceptable
Spectrometer	752	1	3.0	Acceptable